A synergistic blend of Echinacea, Goldenseal, Myrrh, and Oregon Grape Root. Vital Four narrows BioPure's Viressence tincture down to four ingredients which may benefit diabetes patients as it regulates blood sugar metabolism while boosting the immune system.
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BioPure's herbal tinctures are each chosen for its specific health-supporting properties and strictly selected from the finest harvests. BioPure selects products grown in an environment free of fertilizers and insecticides. Our formulas are based on herbs with a proven historical track record in traditional healing therapies that have been used for centuries.
Inteded for internal or external use†.
Please Note: Not intended for use for children or during pregnancy or when breast feeding except under the care of a licensed medical practitioner.
Echinacea and Goldenseal are both well known as stimulants of the immune system and are often combined in supplements intended to fight colds, flus, and upper respiratory tract infections (15,16,17,18). Research has shown that each herb stimulates different types of antibodies in mice, which may be one reason they work well together (19). Goldenseal contains berberine, an important alkaloid which has been getting a lot of attention lately in relation to its ability to lower blood glucose levels and stimulate sensitivity to insulin in Type 2 diabetic patients (20). It is also a potent anti-inflammatory agent (21).
Oregon Grape Root comes from an evergreen shrub native to the American Northwest. It is known to have antibacterial, antimicrobial, antiviral, and antifungal properties (22,23,24). Like Goldenseal, one of the constituent alkaloids in Oregon Grape Root is berberine, and because Goldenseal is becoming harder to find due to overharvesting, Oregon Grape Root is coming into demand for its berberine content and its beneficial effects on glucose and lipid metabolism (22,25,26,27). The herb is classified as “bitter” and has been traditionally used to stimulate digestion and address a variety of intestinal and urinary tract disorders, and as a liver and gall bladder tonic (22). Oregon Grape Root has also shown effectiveness in helping to reduce inflammation and symptoms of skin conditions such as acne, eczema, and psoriasis (28,29).
Myrrh is one of history’s oldest and most important resins, being used for a wide variety of medicinal and spiritual purposes. Like Oregon Grape, Myrrh is classified as “bitter” and is believed to have antiseptic astringent qualities, useful in stimulating digestion, blood circulation, dispersion of swelling, and as an expectorant and decongestant (36). Modern research supports its anti-inflammatory properties (37), antibacterial, antifungal, and even anaesthetic activity (38).
(15)Shah SA, Sander S, White CM, Rinaldi M, Coleman DI. Evaluation of Echinacea for the prevention and treatment of the common cold: a meta-analysis. The Lancet-Infectious Diseases. Volume 7, Issue 7, July 2007, Pages 473–480.
(16)Schoop R, Klein P, Suter A, Johnston SL. Echinacea in the prevention of induced rhinovirus colds: A meta-analysis. Clinical Therapeutics. Volume 28, Issue 2, February 2006, Pages 174–183.
(17)Pleschka S, Stein M, Roland Schoop R and Hudson JB.Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian Influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV). Virology Journal 2009, 6:197.
(18)Bergner P. Goldenseal and the common cold: The antibiotic myth. Medical Herbalism: A Journal for the Clinical Practitioner. Volume 8, No 4, Winter 1996-1997.
(19)Rehman J, Dillow JM, Carter SM, Chou J, Le B, Maisel AS. Increased production of antigen-specific immunoglobulins G and M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis. Immunol Lett. 1999 Jun 1;68(2-3):391-5.
(20)Yin J, Xing H, Ye J. Efficacy of Berberine in Patients with Type 2 Diabetes. Metabolism. 2008 May; 57(5): 712–717.
(23)Slobodníková L, Kost'álová D, Labudová D, Kotulová D, Kettmann V. Antimicrobial activity of Mahonia aquifolium crude extract and its major isolated alkaloids. Phytother Res. 2004 Aug;18(8):674-6.
(24)Volleková A, Kost'álová D, Kettmann V, Tóth J. Antifungal activity of Mahonia aquifolium extract and its major protoberberine alkaloids. Phytother Res. 2003 Aug;17(7):834-7.
(25)Hao Zhang, Jing Wei, Rong Xue, Jin-Dan Wu, Wei Zhao, Zi-Zheng Wang, Shu-Kui Wang, Zheng-Xian Zhou, Dan-Qing Song, Yue-Ming Wang, Huai-Ning Pan, Wei-Jia Kong, Jian-Dong Jiang. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Metabolism - Clinical and Experimental. Volume 59, Issue 2 , Pages 285-292, February 2010.
(26)Yin J, Xing H, Ye J. Efficacy of Berberine in Patients with Type 2 Diabetes. Metabolism. 2008 May; 57(5): 712–717.
(27)Kong W, Wei J, Abidi P, Lin M, Inaba S, Li C, Wang Y, Wang Z, Si S, Pan H, Wang S, Wu J, Wang Y, Li Z, Liu J, Jiang JD. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med. 2004 Dec;10(12):1344-51.
(28)Dattner AM. From medical herbalism to phytotherapy in dermatology: back to the future. Dermatologic Therapy. Volume 16, Issue 2, pages 106–113, June 2003. ACNE
(29)Gulliver WP, Donsky HJ. A report on three recent clinical trials using Mahonia aquifolium 10% topical cream and a review of the worldwide clinical experience with Mahonia aquifolium for the treatment of plaque psoriasis. Am J Ther. 2005 Sep-Oct;12(5):398-406.
(37)Min-Sun Kim, Gi-Sang Bae, Kyoung-Chel Park, Bon Soon Koo, Byung-Jin Kim, Hye-Jin Lee, Sang-Wan Seo, Yong Kook Shin, Won-Seok Jung, Jung-Hee Cho, Youn-Chul Kim, Tae-Hyeon Kim, Ho-Joon Song, and Sung-Joo Park. Myrrh Inhibits LPS-Induced Inflammatory Response and Protects from Cecal Ligation and Puncture-Induced Sepsis. Evid Based Complement Alternat Med. 2012; 2012: 278718.
(38)Dolara P, Corte B, Ghelardini C, Pugliese AM, Cerbai E, Menichetti S, Lo Nostro A. Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh. Planta Med. 2000 May;66(4):356-8.
† or use as directed by your healthcare practitioner.
* Our products are not intended to diagnose, treat, cure or prevent any disease and are designed to be used as part of an overall health plan with your authorized healthcare provider. Individuals taking food supplements or have an underlying health condition should consult with their authorized healthcare provider before using these products. We suggest that you consult your authorized healthcare provider if you have any health problems and require a medical diagnosis, medical advice or treatment. Statements herein have not been evaluated by the FDA. We do not recommend any of our natural products to be used for small children without the guidance of a licensed healthcare provider. We do not recommend that any of our products be used while breastfeeding, while pregnant or trying to become pregnant.
** Allergy test by using trace amount on skin and observing for 24 hours. Continue allergy test for consumption with trace amount and observe for 24 hours. Stop use of product if adverse reactions occur with ongoing use.
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