Astaxanthin is made in a base of wild, certified-sustainable salmon oil.
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BioPure Astaxanthin Capsules
Natural Astaxanthin in a base of Wild Sockeye Salmon Oil, offered in a bottle of 90 softgel capsules.
Astaxanthin has been found to be one of the most powerful antioxidants known. BioPure has harnessed this power in a base of Wild Alaskan Sockeye Salmon Oil to add the nutritional benefits of omega-3 fatty acids.
Photoprotective and Skin Support*
Intended for internal use. Take one softgel daily†.
Please Note: Do not use when pregnant or nursing, or for small children unless recommended by your practitioner.
Astaxanthin, pronounced “asta-zan-thin”, is a richly colored red-orange pigment within the carotenoid family of compounds, and is found in certain microscopic freshwater algae, yeast, shrimp, and krill. Astaxanthin is responsible for the reddish color of salmon flesh, lobster shells, and the feathers of some birds, such as flamingos. BioPure’s Astaxanthin is obtained from a particular algae known as Haematococcus pluvialis. The algae is grown under controlled conditions in Hawaii, and the Astaxanthin is isolated from the algae using C02 supercritical extraction. This is a highly efficient, environmentally friendly, and solvent-free process, resulting in a pure and potent bioactive product.
Astaxanthin has been found to be one of the most powerful antioxidants known, with outstanding capacity both as a singlet oxygen quencher and as a scavenger of free radical oxygen.1,2 The compound has an elongated chemical structure with a non-polar series of alternating single and double conjugated carbon bonds in the center, and polar ionone rings at either end. Its unique structure allows Astaxanthin to orient itself transversely across the membrane of a typical cell and participate in a variety of antioxidant reactions3,4. Astaxanthin’s singlet oxygen quenching capacity has been found to be 550 times stronger than Vitamin E5 and green tea,2 and as much as 6000 times greater than Vitamin C.2
Singlet oxygen quenching is particularly important in protecting the skin and eyes against UVA-induced radiation damage,6,7,8 and some studies suggest that dietary supplementation with Astaxanthin may aid in preventing or delaying sunburn.9,10 Astaxanthin has also been found to decrease fine lines and wrinkles and improve elasticity and skin tone.11,12
In the case of Astaxanthin, beauty is more than skin deep. Because oxidative stress is at the root of so many health problems, numerous research studies with Astaxanthin are suggesting a myriad of potential health benefits. Astaxanthin may enhance physical stamina and performance in sports by lessening lactic acid buildup, increasing energy efficiency, and aiding in muscle tissue repair.13,14 Increased visual acuity and relief of eye fatigue was reported.14,15,16The body’s immune response may be improved17. It was found to increase serum insulin and reduce blood glucose levels in diabetic mice.18 It showed a protective effect on rat liver cells and nervous system function.13,19 Memory in both mice20 and humans21 showed improvement. Cardiovascular benefits include inhibition of oxidation of LDL (the ‘bad’ cholesterol) and raising levels of HDL (the ‘good’ cholesterol), and improving bloodflow.22,23 Lowering oxidative stress can have an anti-inflammatory effect, which is directly related to atherosclerotic cardiovascular disease.24 Anti-bacterial activity and anti-inflammatory effects improved symptoms of chronic gastritis and ulcers associated with Helicobacter pylori.25,26And cancer research on animals showed that Astaxanthin was able to inhibit the growth of mammary tumors27, as well as bladder, colon, and oral cancer cell proliferation.28
Unlike most antioxidants, Astaxanthin is fat-soluble. Within our bodies, it is absorbed in the intestine and can be stored in the liver and fatty tissues. It has been found thatAstaxanthin is more efficiently absorbed if taken with food containing fats,29 particularly salmon. Interestingly, it was also found that the bioavailability was significantly decreased in smokers.30
To ensure you the strongest and most thorough antioxidant benefits, BioPure’s Astaxanthin is encapsulated in 260 mg of wild Alaskan Sockeye Salmon oil, plus a small amount of non-GMO, hi-oleic safflower oil. Vitamin E mixed tocopherols derived from soybeans are added to protect the oils from oxidation during storage. This may leave small traces of soy fatty acids, but soy proteins, which are the part of soy most commonly responsible for allergic reactions. To complete the benefit package, BioPure’s Astaxanthin also contains Vitamins A and D, plus the beneficial omega-3 fatty acids EPA and DHA, as well as Lutein, a yellow-colored carotenoid that is very important to eye health. In addition, several studies have tested the safety of taking oral supplementation of Astaxanthin and shown no harmful side effects.21, 31
1 Miki W. Biological functions and activities of animal carotenoids. Pure & Appl. Chem. Vol. 63, No. 1, pp. 141-146, 1991.
2 Nishida Y, Yamashita E, and Miki W. Quenching Activities of Common Hydrophilic and Lipophilic Antioxidants against Singlet Oxygen Using Chemiluminescence Detection System. Carotenoid Science, Vol.11, 2007, 16-20.
3 Kidd P. Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med Rev. 2011 Dec;16(4):355-64.
4 McNulty HP, Byun J, Lockwood SF, Jacob RF, Mason RP. Differential effects of carotenoids on lipid peroxidation due to membrane interactions: X-ray diffraction analysis. Biochim Biophys Acta. 2007 Jan;1768(1):167-74.
5Shimidzu, Gogo, Miki, Carotenoids as Singlet Oxygen Quenchers in Marine Organisms. Fisheries Science. 62(1), 134-137, 1995.
6 Camera E, Mastrofrancesco A, Fabbri C, Daubrawa F, Picardo M, Sies H, Stahl W. Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. Exp Dermatol. 2009 Mar;18(3):222-31.
7 Lyons, NM and O’Brien, NM. Modulatory effects of an algal extract containing astaxanthin on UVA-irradiated cells in culture. Dermatol. Sci. 2002, 30, 73-84.
8 O'Connor I, O'Brien N. Modulation of UVA light-induced oxidative stress by beta-carotene, lutein and astaxanthin in cultured fibroblasts. J Dermatol Sci. 1998 Mar;16(3):226-30.
9 Higuera-Ciapara I, Felix-Venezuela LF and Goycoolea FM. Astaxanthin: A Review of its Chemistry and Applications. Critical Reviews in Food Science and Nutrition, 46:185–196 (2006).
10 Camera E, Mastrofrancesco A, Fabbri C, Daubrawa F, Picardo M, Sies H, Stahl W. Astaxanthin, canthaxanthin and β-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. Experimental Dermatology. Volume 18, Issue 3, pages 222–231, March 2009.
11 Yamashita E. The Effects of a Dietary Supplement Containing Astaxanthin on Skin Condition. Carotenoid Science. Vol.10, 2006, 91-95.
13 Yuan JP, Peng J, Yin K, Wang JH. Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae. Mol Nutr Food Res. 2011 Jan;55(1):150-65.
14 Sawaki K, Yoshigi H, Aoki K, Koikawa N. et al. Sports Performance Benefits from Taking Natural Astaxanthin Characterized by Visual Acuity and Muscle Fatigue Improvement in Humans. Journal of Clinical Therapeutics & Medicines. 2002, Vol 18:No 9, 1085-1100.
15 Yasunori N, Miharu M, Hiroki T, Shigeaki O. The supplementation effect of Astaxanthin on Accomodation and Asthenopia. Journal of Clinical Therapeutics & Medicines. 2006, Vol 22:No 1, 41-54.
16 Ohgami K, Shiratori K, Kotake S, Nishida T, Mizuki N, Yazawa K and Ohno S. Effects of Astaxanthin on Lipopolysaccharide-Induced Inflammation In Vitro and In Vivo. Invest. Ophthalmol. Vis. Sci. June 2003 vol. 44 no. 6, 2694-2701.
17 Park JS, Chyun JH, Kim YK, Line LL and Chew BP. Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutrition & Metabolism 2010, 7:18.
18 Uchiyama K, Naito Y, Hasegawa G, Nakamura N, Takahashi J, Yoshikawa T. Astaxanthin protects -cells against glucose toxicity in diabetic db/db mice. Redox Report, Vol. 7, No. 5, 2002, 290-293.
19 Kang JO, Kim SJ, Kim H. Effect of astaxanthin on the hepatotoxicity, lipid peroxidation and antioxidative enzymes in the liver of CCl4-treated rats. Methods Find Exp Clin Pharmacol. 2001 Mar;23(2):79-84.
20 Zhang X, Pan L, Wei X, Gao H, Liu J. Impact of astaxanthin-enriched algal powder of Haematococcus pluvialis on memory improvement in BALB/c mice. Environ Geochem Health. 2007 Dec;29(6):483-9.
21 Satoh A, Tsuji S, Okada Y, Murakami N, Urami M, Nakagawa K, Ishikura M, Katagiri M, Koga Y and Shirasawa T. Preliminary Clinical Evaluation of Toxicity and Efficacy of A New Astaxanthin-rich Haematococcus pluvialis Extract. J Clin Biochem Nutr. 2009 May; 44(3): 280–284.
22 Fassett RG, Coombes JS. Astaxanthin: Potential Therapeutic Agent in Cardiovascular Disease. Mar. Drugs 2011, 9, 447-465.
23 Guerin M, Huntley ME and Olaizola M. Haematococcus astaxanthin: applications for human health and nutrition. TRENDS in Biotechnology. Vol.21 No.5 May 2003, 210-216.
24 Kritchevsky SB. Beta-Carotene, Carotenoids and the Prevention of Coronory Heart Disease. J. Nutr. January 1, 1999 vol. 129 no. 1 5-8.
25 Wang X, Willen R, Wadstrom T. Astaxanthin-rich algal meal and vitamin C inhibit Helicobacter pylori infection in BALB/cA mice. Antimicrob Agents Chemother. 2000 Sep;44(9):2452-7.
26 Bennedsen M, Wang X, Willén R, Wadstrom T, Anderson LP. Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunology Letters. Volume 70, Issue 3, 1 December 2000, Pages 185–189
27 Chew BP, Park JS, Wong MW, Wong TS. A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo. Anticancer Res. 1999 May-Jun;19(3A):1849-53.
28 Tanaka, T. et al. (1995) Suppression of azomethane-induced rat colon carcinogenesis by dietary administration of naturally occurring xanthophylls astaxanthin and canthaxanthin during the postinitiation phase. Carcinogenesis 16, 2957–2963.
29 Odeberg JM, Lignell A, Pettersson A, Hoglund P. Oral bioavailability of the antioxidant astaxanthin in humans is enhanced by incorporation of lipid based formulations. European Journal of Pharmaceutical Sciences 19 (2003) 299-304.
30 Okada Y, Ishikura M, Maoka T. Bioavailability of astaxanthin in Haematococcus algal extract: the effects of timing of diet and smoking habits. Biosci Biotechnol Biochem. 2009 Sep;73(9):1928-32.
31 Spiller GA, Dewell A. Safety of an Astaxanthin-Rich Haematococcus pluvialis Algal Extract: A Randomized Clinical Trial. Journal of Medicinal Food. March 2003, 6(1): 51-56.
32 Shigeru Maeda, Katsuhiro Kusadome, Hiroyuki Arima, Akira Ohki, Kensuke Naka. Biomethylation of arsenic and its excretion by the alga Chlorella vulgaris. Applied Organometallic Chemistry. Volume 6, Issue 4, pages 407–413, July 1992.
† or use as directed by your healthcare practitioner.
* Our products are not intended to diagnose, treat, cure or prevent any disease and are designed to be used as part of an overall health plan with your authorized healthcare provider. Individuals taking food supplements or have an underlying health condition should consult with their authorized healthcare provider before using these products. We suggest that you consult your authorized healthcare provider if you have any health problems and require a medical diagnosis, medical advice or treatment. Statements herein have not been evaluated by the FDA. We do not recommend any of our natural products to be used for small children without the guidance of a licensed healthcare provider. We do not recommend that any of our products be used while breastfeeding, while pregnant or trying to become pregnant.
** Allergy test by using trace amount on skin and observing for 24 hours. Continue allergy test for consumption with trace amount and observe for 24 hours. Stop use of product if adverse reactions occur with ongoing use.
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