BioPure ALTHEASTM Suppository
A proprietary blend of Cocoa Butter and Green Coffee Extract; 30 rectal suppositories per jar.
Each product in the line of BioPure suppositories is made with the purest, most high-quality, high antioxidant, food-grade Cocoa Butter, with the addition of select BioPure products.
See our Research & More Information below to learn more about our ALTHEASTM Suppository.
Our rectal suppositories come with complete step-by-step directions for use†.
A proprietary blend of Green Coffee Extract and 100% food grade cocoa butter.
Please Note: We do not recommend any of our natural products to be used in the treatment of small children without the guidance of a licensed healthcare provider. We do not recommend that any of our products be used while nursing, while pregnant or trying to become pregnant.
Allergy test by using trace amount on skin and observing for 24 hours. Stop use of product if adverse reactions occur with ongoing use.
Research & More Information
BioPure’s Altheas™ suppositories contain a base of pure 100% organic cocoa butter with the addition of one gram of green bean coffee extract. The primary health functions associated with this formula are antioxidant, gastrointestinal and detoxification support, liver health, energy boost, and weight management benefits.
Suppositories provide a convenient means of delivery for substances either directly to local vaginal or rectal tissues, or to pathways of systemic absorption. The mucous membranes of the rectum have a rich blood supply and medicines or other herbal substances can be readily absorbed and delivered to the circulatory system. Oral administration of medicines may not always be possible if a patient is incapable of swallowing because they are nauseous, unconscious, or uncooperative–as in the case of a small child. In some cases, more absorption of a medicine can occur through the rectal tissues than orally, because rectal absorption bypasses initial digestion in the gut and delays processing and breakdown by the liver (1,2).
Cocoa butter is a vegetable fat that comes from the fermented, roasted, and crushed seeds of the cocoa plant. This rich emollient is packed with vitamins, minerals, and bioflavonoids, and has been used for hundreds of years to soothe and moisturize the skin, heal wounds and irritations, minimize stretch marks in pregnant women, and to treat vaginal, respiratory and bowel disorders (3). Studies have shown it to be extremely helpful in speeding the healing of serious burns (4). Cocoa butter’s health benefits stem from potent antioxidant abilities attributable to its high flavonoid content (12-18%). It has been shown to encourage anti-inflammatory reactions, stimulate circulation, and support the immune system (5). Studies have also found cocoa butter to inhibit low-density lipoprotein (LDL) oxidation and platelet aggregation (4). BioPure uses a food grade cocoa butter that is 100% organic, undeodorized and unbleached. The minimal amount of processing that it undergoes preserves the highest antioxidant content possible for your health benefit. It also has a wonderful chocolaty aroma. Cocoa butter is solid at room temperature, but melts easily in the body, and its antioxidant content makes it a highly stable emollient that is very resistant to rancidity. All of these properties make cocoa butter an excellent ingredient for its wide use today in skin creams, lotions, soaps, hair products, suppositories, and as a main component of well-loved chocolates.
The green coffee beans used in producing the extract in our suppositories come from organic Coffea arabica plants that contain the highest amounts of beneficial phenols known as chlorogenic acids (CGA). CGA are undergoing a lot of research because of their health-promoting antioxidant and anti-inflammatory effects. They have been associated with reducing blood pressure (6,7) and cholesterol, and lowering the risk of fatty liver disease (8,9,10). By helping to increase the flow of bile, CGA may also support the body in reducing the risk of gallstone formation (10). Green bean coffee extract also appears to be involved in activation of one of the body’s antioxidant response detoxification pathways (11), and in the reduction of blood glucose in Type 2 diabetics (12). Perhaps the most talked about effect of green bean coffee extract is its promising ability to help reduce weight. The chlorogenic acid in green coffee beans appears to have a beneficial effect on fat metabolism and obesity-related hormones, and may be of assistance to those on weight management programs (13,14,15).
Research has discovered that when coffee beans are exposed to boiling water, a potentially harmful substance known as cafestol is released into the oils of the brew. Cafestol is a type of terpene and appears to have the negative effect of raising cholesterol (16). Roasting has been found to destroy some of the chlorogenic acids present in the beans (17). By not boiling or roasting, BioPure’s coffee extract is prepared to maximize the benefits and minimize the negative effects of our high quality green coffee beans.
(1) Choonara IA. Giving drugs per rectum for systemic effect. Archives of Disease in Childhood. 62(8), 771-2.
(2) van Hoogdalem E, de Boer AG, Breimer DD. Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs. Clin Pharmacokinet. 1991 Jul;21(1):11-26.
(3) Dillinger TL, Barriga P, Escárcega S, Jimenez M, Salazar Lowe D, and Grivetti LE. Food of the Gods: Cure for Humanity? A Cultural History of the Medicinal and Ritual Use of Chocolate. J. Nutr. August 1, 2000 vol. 130 no. 8 2057S-2072S
(4) Lamuela-Raventós RM et al. Review: Health Effects of Cocoa Flavonoids. Food Science and Technology International. June 2005 vol. 11 no. 3 159-176.
(5) David L. Katz, Kim Doughty, and Ather Ali. Cocoa and Chocolate in Human Health and Disease. Antioxidants & Redox Signaling. November 15, 2011, 15(10): 2779-2811.
(6) Kozuma K, Tsuchiya S, Kohori J, Hase T, Tokimitsu I. Antihypertensive effect of green coffee bean extract on mildly hypertensive subjects. Hypertens Res. 2005 Sep;28(9):711-8.
(7) Suzuki A, Yamamoto N, Jokura H, Yamamoto M, Fujii A, Tokimitsu I, Saito I. Chlorogenic acid attenuates hypertension and improves endothelial function in spontaneously hypertensive rats. J Hypertens. 2006 Jun;24(6):1065-73.
(8) Wan CW, Wong CN, Pin WK, Wong MH, Kwok CY, Chan RY, Yu PH, Chan SW. Chlorogenic Acid Exhibits Cholesterol Lowering and Fatty Liver Attenuating Properties by Up-regulating the Gene Expression of PPAR-α in Hypercholesterolemic Rats Induced with a High-Cholesterol Diet. Phytother Res. 2012 Jun 6. doi: 10.1002/ptr.4751.
(9) Xu Y, Chen J, Yu X, Tao W, Jiang F, Yin Z, Liu C. Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice. Inflamm Res. 2010 Oct;59(10):871-7.
(10) Subhuti Dharmananda, Ph.D.. Chlorogenic Acid for Healthy Liver and Gallbladder Function. Institute for Traditional Medicine, Portland, Oregon. April 2006.
(11) Boettler U, Volz N, Pahlke G, Teller N, Kotyczka C, Somoza V, Stiebitz H, Bytof G, Lantz I, Lang R, Hofmann T, Marko D. Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo. Molecular Nutrition & Food Research. Volume 55, Issue 5, pages 798–802, May 2011.
(12) Ong KW, Hsu A, Tan BKH (2012) Chlorogenic Acid Stimulates Glucose Transport in Skeletal Muscle via AMPK Activation: A Contributor to the Beneficial Effects of Coffee on Diabetes. PLoS ONE 7(3): e32718. doi:10.1371/journal.pone.0032718.
(13) Hiroshi Shimoda, Emi Seki, and Michio Aitani. Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice. BMC Complement Altern Med. 2006; 6:9.
(14) Cho AS, Jeon SM, Kim MJ, Yeo J, Seo KI, Choi MS, Lee MK. Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice. Food Chem Toxicol. 2010 Mar;48(3):937-43.
(15) New evidence on effects of green coffee beans in weight loss. American Chemical Society March 27, 2012 press release.
(16) Ricketts ML, Boekschoten MV, Kreeft AJ, Hooiveld GJEJ, Moen CJA, Müller M, Frants RR, Kasanmoentalib S, Post SM, Princen HMG, Porter JG, Katan MB, Hofker MH and Moore DD. The Cholesterol-Raising Factor from Coffee Beans, Cafestol, as an Agonist Ligand for the Farnesoid and Pregnane X Receptors. Molecular Endocrinology, July 1, 2007 vol. 21 no. 7 1603-1616 .
(17) Moon JK, Yoo HS, Shibamoto T. Role of roasting conditions in the level of chlorogenic acid content in coffee beans: correlation with coffee acidity. J Agric Food Chem. 2009 Jun 24;57(12).
† or use as directed by your healthcare practitioner.
* Our products are not intended to diagnose, treat, cure or prevent any disease and are designed to be used as part of an overall health plan with your authorized healthcare provider. Individuals taking food supplements or have an underlying health condition should consult with their authorized healthcare provider before using these products. We suggest that you consult your authorized healthcare provider if you have any health problems and require a medical diagnosis, medical advice or treatment. Statements herein have not been evaluated by the FDA. We do not recommend any of our natural products to be used for small children without the guidance of a licensed healthcare provider. We do not recommend that any of our products be used while breastfeeding, while pregnant or trying to become pregnant.
** Allergy test by using trace amount on skin and observing for 24 hours. Continue allergy test for consumption with trace amount and observe for 24 hours. Stop use of product if adverse reactions occur with ongoing use.